In vitro antimicrobial activity of plants used in traditional medicine in Gurage and Silti Zones, south central EthiopiaTeka A, Rondevaldova J, Asfaw Z, Demissew S, Van Damme P, Kokoska L, Vanhove W
BMC Complement Altern Med. 2015 Aug 18;15:286
PubMed Central PMC4539890
Investigators at Ghent University, Addis Ababa University and Czech University of Life Sciences Prague conducted in vitro antimicrobial analysis of medicinal plant species selected according to their traditional medicinal uses in south central Ethiopia.
From the Background:
“Numerous biochemical compounds obtained from medicinal plants possess important antimicrobial properties. Application of these compounds is preferred over synthetic drugs as they have long been used in traditional medicine and are considered safe to humans. New and effective antimicrobials identified from plants can consequently be considered in development of new drugs to combat problems associated with drug resistance. Using effective plant extracts to control human diseases has the additional advantage of low production cost, minimal environmental damage and higher accessibility to rural communities. Hence, medicinal plants are expected to be the future alternative source of new antimicrobial products.”
Based on use reports of local informants and traditional herbalists from the study area for treatment of ailments caused by microbial agents, the team selected 15 plant species for analysis: Apodytes dimidiata, Asparagus africanus, Bersama abyssinica, Cucumis ficifolius, Gladiolous abyssinicus, Guizotia schimperi, Lippia adoensis, Olinia rochetiana, Pavonia urens, Premna schimperi, Pittosporum viridiflorum, Polygala sadebeckiana, Sida rhombifolia, Solanum incanum and Thunbergia ruspolii.
The in vitro analysis found that A. africanus, G. schimperi, L. adoensis and P. schimperi were active against Candida albicans, Enterococcus faecalis and Staphylococcus aureus. In particular, strong antibacterial activity was observed for G. schimperi extract against 17 resistant and sensitive Staphylococcus strains, at a concentration comparable to standard antibiotics.
The authors recommend that the usefulness of these plants, in particular G. schimperi, should be confirmed through further phytochemical and toxicity analyses.
Read the complete article at PubMed Central.
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