Meta-Analysis: Coffee Consumption and Cancer Risk

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Yu X, Bao Z, Zou J, Dong J.
Coffee consumption and risk of cancers: a meta-analysis of cohort studies.
BMC Cancer. 2011 Mar 15;11:96.
PubMed PMID: 21406107

Investigators at Fudan University, Shanghai, undertook a meta-analysis of 59 studies of relative risk of various cancers among coffee drinkers. Cohorts included in the meta-analysis were from Europe (Norway, Denmark, Sweden, France, Finland, and Netherlands), North America (Canada and the United States), and Asia (Japan and Singapore).

Noting that coffee is one of the most widely consumed beverages in the world, and that roasted coffee is a complex mixture of more than a thousand chemicals, the authors limited their meta-analysis to studies of coffee instead of all sources of caffeine.

From the conclusion:

“All in all, our meta-analysis including 40 prospective cohort studies confirmed that coffee drinking have no harmful effect. Instead, coffee consumption is inversely associated with the risk of bladder, breast, buccal cavity and pharynx, colorectum, endometrium, esophagus, hepatocellular, leukemia, pancreas, and prostate cancers.”

Full free text is available via PubMed.

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