Mahavorasirikul W, Viyanant V, Chaijaroenkul W, et al. Cytotoxic activity of Thai medicinal plants against human cholangiocarcinoma, laryngeal and hepatocarcinoma cells in vitro. BMC Complement Altern Med. 2010 Sep 28;10:55.
[PubMed PMID: 20920194; PubMed Central PMCID: PMC2956707.]
Noting that cholangiocarcinoma is a serious public health problem in Thailand with increasing incidence and mortality rates, researchers from Thammasat University investigated cytotoxic activities of crude ethanol extracts of a total of 28 plants and 5 recipes used in Thai folklore medicine against human cholangiocarcinoma (CL-6), human laryngeal (Hep-2), and human hepatocarcinoma (HepG2) cell lines in vitro.
From the Conclusions:
“Results obtained from this study indicate that 6 out of a total of 28 plants and 5 recipes (Atractylodes lancea, Kaempferia galangal, Zingiber officinale, Piper chaba, Mesua ferrea, and Pra-Sa-Prao-Yhai recipe) used in Thai folklore medicine exhibited promising cytotoxic activity against CL-6 human cholangiocarcinoma cell line… Further investigation of all the six extracts for their cytotoxic activity against cholangiocarcinoma in hamster model is underway to fully assess the anticancer activity in vivo.”
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